Analysis of the primary presenting symptoms and hematological findings of COVID-19 patients in Bangladesh

  • Abu Taiub Mohammed Mohiuddin Chowdhury Department of Gastroenterology, First affiliated hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, P.R.China
  • Md Rezaul Karim Biomedical Research Institute of the Hubei University of Medicine, Shiyan, P.R.China
  • HM Hamidullah Mehedi Chattogram General Hospital, Chattogram, Bangladesh
  • Mohammad Shahbaz Chakoria Upazilla Health Complex, Cox’s Bazar. Bangladesh
  • Md Wazed Chowdhury Civil Surgeon’s Office, Chattogram, Bangladesh
  • Guo Dan Department of Gastroenterology, First affiliated hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, P.R.China
  • Shuixiang He Department of Gastroenterology, First affiliated hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, P.R.China
Keywords: SARS-CoV-2, COVID-19, real-time RT-PCR, COVID-19 symptoms, COVID-19 hematological findings, Bangladesh

Abstract

Introduction: SARS-Cov-2 infection or COVID-19 is a global pandemic. In this manuscript, we investigated the primary symptoms and basic hematological presentations of SARS-CoV-2 infection among the Bangladeshi patients.

Methodology: This was a multicentre cross-sectional study done on COVID-19 patients tested positive by RT PCR in Bangladesh. Clinical features of mild to moderate degree of COVID-19 patients; hematological and biochemical admission day laboratory findings of moderate to severe degree hospitalized COVID-19 patients were analyzed.

Results: COVID-19 patients in Bangladesh commonly presented with fever, cough, fatigue, shortness of breath, and sore throat. But symptoms like myalgia, diarrhea, skin rash, headache, Abdominal pain/cramp, nausea, vomiting, restlessness, and a higher temperature of >100°F have a greater presentation rate and more frequent than other published studies. CRP and Prothrombin time was found to increase in all the patients. Serum ferritin, ESR, SGPT, and D-Dimer were increased among 53.85%, 80.43, 44%, and 25% patients. 17.39% of the patients had leucocytosis and neutrophilia, 28.26% presented with lymphocytopenia, and 62.52% had mild erythrocytopenia. The difference between the decrease hemoglobin count (higher in the male) and increased SGPT (higher in female) against gender was significant.

Conclusions: Our study had evaluated a different expression in presenting symptoms of COVID-19 patients in Bangladesh. CRP, Prothrombin time, serum ferritin, ESR, SGPT, D-Dimer, erythrocytopenia, and lymphocytopenia can be assessments for diagnosis and prognosis of COVID-19 disease. Decrease hemoglobin count (higher in the male) and increased SGPT (higher in female) establish these two markers as a good candidate for diagnostic value against gender.

Author Biography

Shuixiang He, Department of Gastroenterology, First affiliated hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, P.R.China

Professor and Head

Department of Gastroenterology,

First Affiliated Hospital of Xi’an Jiaotong University,

Shaanxi, P.R. China

Published
2021-03-07
How to Cite
1.
Mohiuddin Chowdhury ATM, Karim MR, Mehedi HH, Shahbaz M, Chowdhury MW, Dan G, He S (2021) Analysis of the primary presenting symptoms and hematological findings of COVID-19 patients in Bangladesh. J Infect Dev Ctries 15:214-223. doi: 10.3855/jidc.13692
Section
Coronavirus Pandemic