Clinical and mycological characteristics of keratitis caused by Colletotrichum gloeosporioides: A case report and review of literature

Alireza  Izadi; Mohammad  Soleimani; Roshanak  Daie Ghazvini; Seyed Jamal  Hashemi; Mohssen  Gramishoar; Kazem  Ahmadikia; Mehdi  Aminizadeh; Mohammad  Ghahri; Zohre  Abedinifar; Aleksandra  Barac; Sadegh Khodavaisy

doi:10.3855/jidc.14492

Clinical and mycological characteristics of keratitis caused by Colletotrichum gloeosporioides: A case report and review of literature

Authors

Alireza Izadi Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Mohammad Soleimani Department of Ocular Trauma and Emergency, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran
Roshanak Daie Ghazvini Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Seyed Jamal Hashemi Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Mohssen Gramishoar Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Kazem Ahmadikia Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Mehdi Aminizadeh Department of Ocular Trauma and Emergency, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran
Mohammad Ghahri Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran
Zohre Abedinifar Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran
Aleksandra Barac Clinic for Infectious and Tropical Diseases, Clinical Centre of Serbia, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Sadegh Khodavaisy Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

DOI:

https://doi.org/10.3855/jidc.14492

Keywords:

Colletotrichum gloeosporioides, keratitis, molecular identification

Abstract

Introduction: Colletotrichum species are well-known plant pathogens, which have been increasingly reported as the cause of keratitis or subcutaneous lesions in humans. In this study we reported a rare case of fungal keratitis from Iran and reviewed the literature.

Case Presentation: A 69-year-old man whose right eye was injured by herbal material was examined by slit-lamp biomicroscopy and mycology investigation of corneal scrapings was done. The grown filamentous fungal was identified as Colletotrichum gloeosporioides based on morphological characteristics and DNA sequence of the internal transcribed spacer region. The isolated strain was sensitive to amphotericin B, caspofungin, anidolafungin, micafungin, voriconazole, and relatively resistant to fluconazole, and itraconazole. Patient was successfully treated with voriconazole.

Conclusions: This report highlights that the early and accurate identification and therapy can helpful to management keratitis caused by C. gloeosporioides.

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Published

2021-03-07

How to Cite

Izadi A, Soleimani M, Daie Ghazvini R, Hashemi SJ, Gramishoar M, Ahmadikia K, Aminizadeh M, Ghahri M, Abedinifar Z, Barac A, Khodavaisy S (2021) Clinical and mycological characteristics of keratitis caused by Colletotrichum gloeosporioides: A case report and review of literature. J Infect Dev Ctries 15:301–305. doi: 10.3855/jidc.14492

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Issue

Vol. 15 No. 02: February 2021

Section

Case Reports

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