Anxiety impact during COVID-19: a systematic review

  • Patricia Batista Centro de Biotecnologia e Química Fina (CBQF) – Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Porto, Portugal
  • Vitor Duque Faculdade Medicina da Universidade de Coimbra, Coimbra, Portugal
  • Ana Luzio-Vaz Centro Hospitalar e Universitário de Coimbra (CHUC), Coimbra, Portugal
  • Anabela Pereira Education and Psychology Department, Campus Universitário de Santiago, University of Aveiro, Aveiro, Portugal
Keywords: COVID-19, anxiety, psychological diseases, infections


Introduction: The COVID-19 epidemic has been causing serious physical, but also psychological effects in society. This systematic review sought to identify studies that describe COVID-19 related anxiety, and to understand the impact of anxiety assessment in defining strategies to be implemented in future studies.

Methodology: This systematic review included cross-sectional studies with no publication year limit. It was performed a systematic search through three databases, namely, PubMed, Science Direct and Web of Science using the descriptors “COVID-19” and “anxiety”. PRISMA criteria reporting of systematic reviews and meta-analyses were applied. Eligible articles were selected in accordance with inclusion and exclusion criteria. The inclusion criteria were: research articles related with anxiety measurement during the COVID-19 outbreak; interventions to reduce anxiety; and published in English.

Results: From 44 references, just four scientific articles were accepted for inclusion within this review. These studies were analyzed regarding their sample, methodology, instruments used, and its results.

Conclusions: This systematic review was based on published data at the onset of the pandemic, and it could serve as a basis for the development of implementations plans to improve anxiety disorders. The importance of this theme, the implications and potential directions for future investigations will be discussed.


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How to Cite
Batista P, Duque V, Luzio-Vaz A, Pereira A (2021) Anxiety impact during COVID-19: a systematic review. J Infect Dev Ctries 15:320-325. doi: 10.3855/jidc.12730
Coronavirus Pandemic