A case series of brain abscesses: an eleven-year retrospective single center study

  • Rami Waked Department of Infectious Diseases, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
  • Hassan Tarhini Department of Infectious Diseases, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
  • Hussein Mansour Department of Infectious Diseases, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
  • Gebrael Saliba Department of Infectious Diseases, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
  • Nabil Chehata Department of Infectious Diseases, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
  • Marie Chedid Department of Infectious Diseases, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
  • Elie Haddad Department of Infectious Diseases, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
  • Jacques Choucair Department of Infectious Diseases, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
Keywords: Brain abscess, Stereotactic biopsy, HIV, Antibiotics, patient prognosis

Abstract

Introduction: We lack data on the epidemiology and management of brain abscesses in the Middle East. The aim of this study is to report a case series of brain abscesses admitted at a tertiary care center in Lebanon, between January 2008 and December 2018.

Methodology: This retrospective study aimed at determining the demographic data, treatment, and correlations between different studied variables with prognosis of patients that received treatment.

Results: Forty-one patients (30 males) were included with a median age of 37 years (2-85). The analysis showed that the classic triad of fever, headache and neurologic deficit was only present in 12% of patients on admission. The source of infection was contiguous in 36.5%, post surgical in 32%, and distant in 17% of cases. Stereotactic biopsy was performed in 41.5% of patients, and craniotomy in 19.5%. A microorganism was isolated in 63% of patients (26 cases). The most used antibiotics were carbapenems (46%) and glycopeptides (66%). Eighty percent of patient (33) had a good outcome. A worse prognosis was significantly correlated with immunosuppression and multiple cerebral abscesses.

Conclusions: Brain abscess remains a relatively rare condition.

Published
2021-06-30
How to Cite
1.
Waked R, Tarhini H, Mansour H, Saliba G, Chehata N, Chedid M, Haddad E, Choucair J (2021) A case series of brain abscesses: an eleven-year retrospective single center study. J Infect Dev Ctries 15:791-797. doi: 10.3855/jidc.12816
Section
Original Articles