The emergence of Dengue Fever in Sheikhupura, Pakistan: its seroprevalence and risk factors assessment during 2014-2017

  • Muhammad Uzair Mukhtar State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xujiaping 1, Lanzhou, Gansu, China
  • Maria Mukhtar Department of Biology, Government Degree College for women Shahrukn e Alam, Multan, Pakistan
  • Naveed Iqbal State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xujiaping 1, Lanzhou, Gansu, China
  • Zeeshan Nawaz Department of Microbiology, Government College University Faisalabad, Faisalabad, Pakistan
  • Adil Bhatti Directorate of Malaria Control, Ministry of National Health Services, Regulations and Coordination, Islamabad, Pakistan
  • Fatima Haq Health Department, Government of Punjab, Pakistan
  • Ali Arslan Punjab Livestock and Dairy Development Department, Pakistan
  • Muhammad Rashid Department of Parasitology, Faculty of Veterinary and Animal Sciences, The Islamia University Bahawalpur, Pakistan
Keywords: Dengue, Prevalence, IgM, IgG, Pakistan

Abstract

Introduction: District Sheikhupura encountered its first dengue outbreak in 2014 but lacked serological evidence and reports of risk factors associated with it. To assess this, a hospital-based study was conducted from January 2014 to December 2017.

Methodology: Blood from 333 participants was collected, the serum obtained was tested for IgG and IgM antibodies against DENV using a commercially available ELISA kit.

Results: The results showed that out of all (n= 333) samples tested, 120 were turned up positive for DENV, making an overall prevalence of 36%. Of the 120 confirmed cases, 55% (n = 66) were recorded in 2014, 10% (n = 12) in 2015, 27.5% (n = 33) in 2016, and 7.5% (n = 9) in 2017. It was found that 68.3% (n = 82) were male and 31.7% (n = 38) were female, with 61% (n = 74) patients aged between 11-30 years. The highest prevalence of infection, 94.2% (n = 113), was noted after the rainy season. During the study, the highest number of cases appeared in Ferozewala Tehsil. The factors age, gender, and season were found statistically significant with the prevalence of infection (p < 0.05).

Conclusions: The study is the first report on the detection of dengue in the Sheikhupura district. The survey anticipated its geographical expansion, determined associated risk factors, and suggests active disease surveillance in the area.

Published
2021-09-30
How to Cite
1.
Mukhtar MU, Mukhtar M, Iqbal N, Nawaz Z, Bhatti A, Haq F, Arslan A, Rashid M (2021) The emergence of Dengue Fever in Sheikhupura, Pakistan: its seroprevalence and risk factors assessment during 2014-2017. J Infect Dev Ctries 15:1351-1355. doi: 10.3855/jidc.13976
Section
Brief Original Articles