COVID-19 disease characteristics in different pediatric age groups

  • Eda Kepenekli Marmara University School of Medicine, Pendik Training and Research Hospital. Department of Pediatrics, Division of Pediatric Infectious Diseases, Istanbul, Turkey.
  • Nurhayat Yakut Marmara University School of Medicine, Pendik Training and Research Hospital. Department of Pediatrics, Division of Pediatric Infectious Diseases, Istanbul, Turkey.
  • Zeynep Ergenc Marmara University School of Medicine, Pendik Training and Research Hospital. Department of Pediatrics, Division of Pediatric Infectious Diseases, Istanbul, Turkey.
  • Ömer Aydıner Kartal Dr. Lütfi Kırdar City Hospital. Department of Radiology, Istanbul, Turkey
  • Rabia Can Sarınoğlu Marmara University School of Medicine, Pendik Training and Research Hospital. Department of Medical Microbiology, Istanbul, Turkey.
  • Ayşegül Karahasan Marmara University School of Medicine, Pendik Training and Research Hospital. Department of Medical Microbiology, Istanbul, Turkey.
  • Elif Karakoc-Aydıner Marmara University School of Medicine, Pendik Training and Research Hospital. Department of Pediatrics, Division of Pediatric Allergy and Immunology, Istanbul, Turkey.
  • Aslı Memişoğlu Marmara University School of Medicine, Pendik Training and Research Hospital. Department of Pediatrics, Division of Neonatology, Istanbul, Turkey.
  • Yasemin Gökdemir Marmara University School of Medicine, Pendik Training and Research Hospital. Department of Pediatrics, Division of Pediatric Pulmonology, Istanbul, Turkey
  • Ela Erdem Eralp Marmara University School of Medicine, Pendik Training and Research Hospital. Department of Pediatrics, Division of Pediatric Pulmonology, Istanbul, Turkey
  • Pınar Ergenekon Marmara University School of Medicine, Pendik Training and Research Hospital. Department of Pediatrics, Division of Pediatric Pulmonology, Istanbul, Turkey
  • Bülent Karadağ Marmara University School of Medicine, Pendik Training and Research Hospital. Department of Pediatrics, Division of Pediatric Pulmonology, Istanbul, Turkey
  • Kübra Gökçe Tezel Marmara University School of Medicine, Pendik Training and Research Hospital. Department of Pediatrics, Istanbul, Turkey.
  • Murat Aydın Marmara University School of Medicine, Pendik Training and Research Hospital. Department of Pediatrics, Istanbul, Turkey.
  • Betül Şenyürek Marmara University School of Medicine, Pendik Training and Research Hospital. Department of Pediatrics, Istanbul, Turkey.
  • Perran Boran Marmara University School of Medicine, Pendik Training and Research Hospital. Department of Social Pediatrics, Istanbul, Turkey.
Keywords: Children, COVID-19, pediatric age groups, Turkey

Abstract

Introduction: Little is known about the COVID-19 disease characteristics and differences between different pediatric age groups. This study aimed to investigate the disease characteristics according to age groups.

Methodology: We conducted a retrospective, single-center study of pediatric COVID-19 in a tertiary care hospital in Turkey. The patients were divided into three groups: 15 days-24 months old (Group 1), 25-144 months old (Group 2), and 145-210 months old (Group 3) according to age.

Results: A total of 139 pediatric patients with COVID-19 were examined. Twenty-nine patients (20.9%) were in Group 1, 52 (37.4%) were in Group 2, 58 (41.7%) were in Group 3. Thirty-nine patients (28.1%) were hospitalized. The most common symptoms were cough (55.4%) and fever (51.8%). The median chest X-ray (CXR) score of hospitalized patients was 1 (min 0-max 7), and the median CXR score of outpatients was 1 (min 0-max 6). Fever was significantly more frequent in Group 1, and chest pain was more frequent in Group 3. Group 1 had significantly higher WBC, lymphocyte, thrombocyte counts, AST, LDH, D-dimer, and Troponin T levels but lower hemoglobin, total protein, and albumin levels. The treatment included antibiotics, oseltamivir, hydroxychloroquine, and supportive therapy. Only one patient (0.7%) received non-invasive mechanical ventilatory support.

Conclusions: As we know the clinical course of COVID-19 in children is less severe than in adults. We also found significant differences in both clinical and laboratory findings between different pediatric age groups which supports the theory that disease pathogenesis is highly variable according to age.

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Published
2022-01-31
How to Cite
1.
Kepenekli E, Yakut N, Ergenc Z, Aydıner Ömer, Sarınoğlu RC, Karahasan A, Karakoc-AydınerE, Memişoğlu A, Gökdemir Y, Eralp EE, Ergenekon P, Karadağ B, Tezel KG, Aydın M, Şenyürek B, Boran P (2022) COVID-19 disease characteristics in different pediatric age groups. J Infect Dev Ctries 16:16-24. doi: 10.3855/jidc.15353
Section
Coronavirus Pandemic