Leptospiral infection: a serosurvey in urban and rural communities in Olavarría county, Argentina

  • Mariana Alejandra Rivero Veterinary Research Center of Tandil (CIVETAN) (CICPBA-UNCPBA-CONICET), Tandil, Argentina
  • Exequiel Alejandro Scialfa Agronomy Faculty, UNCPBA, Azul, Argentina
  • Héctor Mario Appendino School of Medicine, UNCPBA, Olavarría, Argentina
  • Melina Barbero School of Medicine, UNCPBA, Olavarría, Argentina
  • Paola Barragán School of Medicine, UNCPBA, Olavarría, Argentina
  • Félix Carlos Martin School of Medicine, UNCPBA, Olavarría, Argentina
  • Betsabé Morón School of Medicine, UNCPBA, Olavarría, Argentina
  • Julia Analia Silva Veterinary Research Center of Tandil (CIVETAN) (CICPBA-UNCPBA-CONICET), Tandil, Argentina
  • Adela Tisnés Faculty of Human Sciences (UNCPBA) CIG- IGEHCS- CONICET, Tandil, Buenos Aires, Argentina
  • Silvia Marcela Estein Veterinary Research Center of Tandil (CIVETAN) (CICPBA-UNCPBA-CONICET), Tandil, Argentina
  • Marcelo Lisandro Signorini Faculty of Veterinary Sciences, National University of the Litoral (CONICET), Esperanza, Argentina
  • Silvia Elena González Ayala School of Medicine, UNCPBA, Olavarría, Argentina
  • Jorge Bolpe Department of Rural Zoonoses, Provincial Bureau of Public Health Medicine, Ministry of Health, Buenos Aires Province, Azul, Argentina
Keywords: Leptospirosis, seroprevalence, risk factors

Abstract

Introduction: Leptospirosis is a neglected zoonotic disease, affecting mainly poor and vulnerable populations.

Methodology: A cross sectional-study was carried out in 557 subjects from Olavarría county (Argentina) to estimate the seroprevalence of leptospirosis and the factors associated with seropositivity. A survey was carried out to obtain clinical and epidemiological data. Serum was tested for anti-leptospiral antibodies by Microscopic Agglutination Test (MAT). Chi-square or Fisher Exact tests were used to assess association between the MAT results and the exploratory variables. For the variables statistically associated, odds ratios (ORs) and 95% confidence intervals (95% CI) were calculated. Individuals from Olavarría city were georeferenced to describe the spatial distribution and to detect clusters of seropositivity for leptospiral antibodies.

Results: The overall prevalence of leptospirosis infection was 7.00%, higher in rural (19.66%) than in urban populations (3.64%) (p < 0.001). Sejroe was the most predominant serogroup in rural communities while Icterohaemorrhagiae was the most prevalent in urban populations. The factors associated with Leptospira infection were the presence of rodents inside households (OR = 3.9) in rural populations, while contact with cats (OR = 4.97) and male gender (OR = 7.75) represented higher risk of infection for the urban ones. Cases with positive serology have been found near Tapalqué stream or in the peripheral areas of Olavarría city.

Conclusions: The results from data obtained during the study period were similar to other reports and demonstrate the importance of continuous epidemiological surveillance system and specific community educational campaigns to prevent the leptospirosis infection in Olavarría county and other communities with similar characteristics especially in rural areas.

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Published
2022-04-30
How to Cite
1.
Rivero MA, Scialfa EA, Appendino HM, Barbero M, Barragán P, Martin FC, Morón B, Silva JA, Tisnés A, Estein SM, Signorini ML, González AyalaSE, Bolpe J (2022) Leptospiral infection: a serosurvey in urban and rural communities in Olavarría county, Argentina. J Infect Dev Ctries 16:608-615. doi: 10.3855/jidc.13154
Section
Original Articles