Clinical and microbiological patterns in critically ill patients with catheter-associated UTI: A report from Iran

Authors

  • Mohammadreza Salehi Research center for antibiotic stewardship and antimicrobial resistance, Department of Infectious Diseases, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
  • Dariush Robati Research center for antibiotic stewardship and antimicrobial resistance, Department of Infectious Diseases, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
  • SeyedAhmad SeyedAlinaghi Iranian Research Center for HIV/AIDS, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran https://orcid.org/0000-0003-3210-7905
  • Arash Seifi Research center for antibiotic stewardship and antimicrobial resistance, Department of Infectious Diseases, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran https://orcid.org/0000-0002-6174-0315
  • Amir Aliramezani Department of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland https://orcid.org/0000-0002-0252-0945
  • Seyed Ali Dehghan Manshadi Iranian Research Center for HIV/AIDS, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran https://orcid.org/0000-0002-0619-2950
  • Pegah Afarinesh Khaki Central laboratory, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran https://orcid.org/0000-0001-8827-285X
  • Fariba Zamani Research center for antibiotic stewardship and antimicrobial resistance, Department of Infectious Diseases, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran https://orcid.org/0000-0002-2615-031X

DOI:

https://doi.org/10.3855/jidc.17084

Keywords:

Catheter-Associated UTI, Enterobacteriaceae, Gram-negative uropathogens, death

Abstract

Introduction: Catheter-associated urinary tract infections (CAUTIs) are among the most common nosocomial infections with different clinical and microbiological characteristics. We studied these characteristics in critically ill patients.

Methodology: This research was a cross-sectional study conducted on intensive care unit (ICU) patients with CAUTI. Patients’ demographic and clinical information and laboratory data, including causative microorganisms and antibiotic susceptibility tests, were recorded and analyzed. Finally, the differences between the patients who survived and died were compared.

Results: After reviewing 353 ICU cases, 80 patients with CAUTI were finally included in the study. The mean age was 55.9 ± 19.1 years, 43.7% were male and 56.3% were female. The mean length of infection development since hospitalisation and hospital stay were 14.7 (3–90) and 27.8 (5–98) days, respectively. The most common symptom was fever (80%). The microbiological identification showed that the most isolated microorganisms were Multidrug-resistant (MDR) Enterobacteriaceae (75%), Pseudomonas aeruginosa (8.8%), Gram-positive uropathogens (8.8%) and Acinetobacter baumannii (5%). Fifteen patients (18.8%) died among whom infections with A. baumannii (75%) and P. aeruginosa (57.1%) were associated with more death (p = 0.005).

Conclusions: Although A. baumannii and P. aeruginosa can be the most important pathogens for death, MDR Enterobacteriaceae are still a serious concern as causes of CAUTIs.

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Published

2023-01-31

How to Cite

1.
Salehi M, Robati D, SeyedAlinaghi S, Seifi A, Aliramezani A, Dehghan Manshadi SA, Afarinesh Khaki P, Zamani F (2023) Clinical and microbiological patterns in critically ill patients with catheter-associated UTI: A report from Iran. J Infect Dev Ctries 17:129–134. doi: 10.3855/jidc.17084

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Section

Brief Original Articles