Diagnosis of leishmaniasis

  • Ehab Kotb Elmahallawy Faculty of Veterinary Medicine, Sohag University, Sohag, Egypt
  • Antonio Sampedro Martinez University Hospital Virgen de las Nieves, Granada, Spain
  • Javier Rodriguez-Granger University Hospital Virgen de las Nieves, Granada, Spain
  • Yannick Hoyos-Mallecot University Hospital Virgen de las Nieves, Granada, Spain
  • Ahamd Agil Faculty of Medicine, University of Granada, Granada, Spain
  • Jose Mari Navarro Mari University Hospital Virgen de las Nieves, Granada, Spain
  • Jose Gutierrez Fernandez University Hospital Virgen de las Nieves, Granada, Spain

Abstract

Leishmaniasis is a clinically heterogeneous syndrome caused by intracellular protozoan parasites of the genus Leishmania. The clinical spectrum of leishmaniasis encompasses subclinical ( not apparent), localized (skin lesion), and disseminated (cutaneous, mucocutaneous, and visceral) infection. This spectrum of manifestations depends on the immune status of the host, on the parasite, and on immunoinflammatory responses. Visceral leishmaniasis causes high morbidity and mortality in the developing world. Reliable laboratory methods become mandatory for accurate diagnosis, especially in immunocompromised patients such as those infected with HIV. In this article, we review the current state of the diagnostic tools for leishmaniasis, especially  the serological test.

Published
2014-08-13
How to Cite
Elmahallawy E, Sampedro Martinez A, Rodriguez-Granger J, Hoyos-Mallecot Y, Agil A, Navarro Mari J, Gutierrez Fernandez J (2014) Diagnosis of leishmaniasis. The Journal Of Infection In Developing Countries 8 (08): 961-972. https://doi.org/10.3855/jidc.4310
Section
Reviews

Keywords

leishmaniasis; diagnosis; serology; HIV co-infection