Abdominal cystic echinococcosis in Bangladesh: a hospital-based study

  • Mohammad Fazal Karim Sir Salimullah Medical College and Mitford Hospital, Dhaka, Bangladesh
  • Enrico Brunetti IRCCS San Matteo Hospital Foundation, University of Pavia, WHO Collaborating Centre for Clinical Management of Cystic Echinococcosis, Pavia, Italy
  • Salimur Rahman Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
  • Christine M. Budke College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station,TX, United States
  • Abu Saleh Mohammad Areef Ahsan BIRDEM General Hospital, Dhaka, Bangladesh
  • Mamun Al-Mahtab Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
  • Khandaker Mahabub Jamal Zaki Sylhet MAG Osmani Medical College, Sylhet, Bangladesh
  • Mohammad Jamshed Alam Shere-E-Bangla Medical College Hospital, Barisal, Bangladesh
  • Sheikh Mohammad Fazle Akbar Toshiba General Hospital, Tokyo, Japan
  • MA Jalil University of Dhaka, Dhaka, Bangladesh
Keywords: cystic echinococcosis, hydatid disease, epidemiology, clinical presentation, ultrasound classification, Bangladesh

Abstract

Introduction: Cystic echinococcosis (CE) is reported from nearly all geographic areas of Bangladesh, but little information is available on its epidemiologic and clinical features. The aim of this study was to describe the clinical manifestations of hepatic and abdominal CE cases presenting to tertiary referral hospitals in Dhaka, Bangladesh.

Methodology: A retrospective study was conducted via chart reviews of hepatic and abdominal CE patients under care at tertiary referral hospitals in Dhaka, Bangladesh, between 2002 and 2011. Age, sex, education level, occupation, urban versus rural residence, drinking water source, history of dog ownership, cyst type and location, and clinical manifestations were recorded for all patients.

Results: Of the 130 patients enrolled, 92 (70.8%) were female and 38 (29.2%) were male. The majority of patients were from rural (76.2%) rather than urban (23.8%) areas. All cases were from the northern part of the country, with no cases reported from the south or southeast. Most patients were between 21 and 40 years of age. A total of 119 patients (91.5%) had cysts only in the liver, with the remaining 8.5% having cysts in both the liver and lungs or in the abdominal cavity. Seventy-six (58.5%) of the hepatic cysts were stage CE1, indicating recent infection.

Conclusions: Active transmission of Echinococcus granulosus appears to be occurring in Bangladesh, as indicated by the high number of CE1 hepatic cysts seen at tertiary care hospitals. Community ultrasound screening studies are warranted to better define the distribution of cases and risk factors for parasite transmission.

Downloads

Download data is not yet available.

Author Biographies

Mohammad Fazal Karim, Sir Salimullah Medical College and Mitford Hospital, Dhaka, Bangladesh

Associate Professor & Head

Department of Hepatology Sir Salimullah Medical College & Mitford Hospital

Enrico Brunetti, IRCCS San Matteo Hospital Foundation, University of Pavia, WHO Collaborating Centre for Clinical Management of Cystic Echinococcosis, Pavia, Italy

Division of Infectious & Tropical Diseases

WHO Collaborating Centre for Clinical Management of Cystic Echinococcosis, Pavia

Director of “Short Course on Abdominal Ultrasound in Tropical Medicine” (www.tropicalultrasound.org)

Salimur Rahman, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

Department of Hepatology


Christine M. Budke, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station,TX, United States

Associate Professor of Epidemiology, Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences

Abu Saleh Mohammad Areef Ahsan, BIRDEM General Hospital, Dhaka, Bangladesh

Department of Critical Care Medicine

Mamun Al-Mahtab, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

Department of Hepatology

Secretary General, Association for the Study of the Liver, Dhaka, Bangladesh (ASLDB)

Member, Central Council, South Asian Association for the Study of the Liver (SAASL)

Deputy Editor-in-Chief, Euroasian Journal of Hepato-Gastroenterology (www.ejohg.com) Specialist in Hepatology with research interest in immune-therapy for hepatitis B and hepatocellular carcinoma

Khandaker Mahabub Jamal Zaki, Sylhet MAG Osmani Medical College, Sylhet, Bangladesh
Department of Hepatology
Mohammad Jamshed Alam, Shere-E-Bangla Medical College Hospital, Barisal, Bangladesh
Department of Hepatology
Sheikh Mohammad Fazle Akbar, Toshiba General Hospital, Tokyo, Japan

Department of Medical Sciences

Works about epidemiology, pathogenesis and control of infectious diseases. Developing immune therapy hepatitis B virus infection

MA Jalil, University of Dhaka, Dhaka, Bangladesh

Department of Statistics, Biostatistics & Informatics


Published
2015-01-15
How to Cite
1.
Karim MF, Brunetti E, Rahman S, Budke CM, Ahsan ASMA, Al-MahtabM, Zaki KMJ, Alam MJ, Akbar SMF, Jalil M (2015) Abdominal cystic echinococcosis in Bangladesh: a hospital-based study. J Infect Dev Ctries 9:070-075. doi: 10.3855/jidc.4934
Section
Original Articles