RSV infection in Istanbul: risk factors and frequency

RSV infection

  • Elif İzci Güllü Dr. Lütfi Kırdar Kartal Education and Research Hospital, Istanbul, Turkey
  • Yasemin Akın Dr. Lütfi Kırdar Kartal Education and Research Hospital, Istanbul, Turkey
  • Ayşe Karaaslan Dr. Lütfi Kırdar Kartal Education and Research Hospital, Istanbul, Turkey
  • Elif Ruşen Vayvada Dr. Lütfi Kırdar Kartal Education and Research Hospital, Istanbul, Turkey
  • Ayşe Ayzıt Atabek Dr. Lütfi Kırdar Kartal Education and Research Hospital, Istanbul, Turkey
  • Fatma Kaya Narter Dr. Lütfi Kırdar Kartal Education and Research Hospital, Istanbul, Turkey

Abstract

Introduction: Respiratory syncytial virus (RSV) is one of the most common causes of acute respiratory infections in all age groups especially under two years. The aim of this study was to investigate the frequency and clinical features of RSV in hospitalized children under two years of age with the diagnosis of lower respiratory tract infections (LRTI) in our region.


Methodology: Between September 2011- May 2013, hospitalized children aged 0-2 years with the diagnosis of viral LRTI, in which nasopharengeal secretions  were tested for the presence of the RSV antigen, were included in this prospective study.


Results: Among the total of 361 hospitalized children who were investigated for RSV antigen, 138 (38%) were female and 223 (62%) were male. The mean age of the group was 5,7±5,1 months (0-24 months). RSV antigen in nasopharyngeal secretions was positive in 68 (19%) of 361 patients. RSV infection was detected significantly higher in December and January (p = 0.003). RSV positivity was significantly higher in patients aged under 6 months (p=0.01), with shorter duration of breastfeeding (p = 0.02), low socioeconomic status (p = 0.02), and also born with spontaneous vaginal delivery (p = 0.007). In RSV(+) LRTI group, children were associated with severe disease than RSV (- LRTI group (p = 0.014).


Conclusions: Since there is lack of data investigating the frequency and the risk factors of RSV respiratory infections in our region, the present study is important for providing new data. Furthermore, this is the second study investigating the correlation between RSV positivity and meteorological conditions in Turkey.

Author Biographies

Elif İzci Güllü, Dr. Lütfi Kırdar Kartal Education and Research Hospital, Istanbul, Turkey

Department of Pediatrics

Yasemin Akın, Dr. Lütfi Kırdar Kartal Education and Research Hospital, Istanbul, Turkey

Department of Pediatrics

Ayşe Karaaslan, Dr. Lütfi Kırdar Kartal Education and Research Hospital, Istanbul, Turkey

Department of Pediatrics

Elif Ruşen Vayvada, Dr. Lütfi Kırdar Kartal Education and Research Hospital, Istanbul, Turkey

Department of Pediatrics

Ayşe Ayzıt Atabek, Dr. Lütfi Kırdar Kartal Education and Research Hospital, Istanbul, Turkey

Department of Pediatrics

Fatma Kaya Narter, Dr. Lütfi Kırdar Kartal Education and Research Hospital, Istanbul, Turkey

Department of Pediatrics

Published
2017-10-07
How to Cite
İzci Güllü E, Akın Y, Karaaslan A, Vayvada E, Atabek A, Kaya Narter F (2017) RSV infection in Istanbul: risk factors and frequency. The Journal Of Infection In Developing Countries 11 (09): 691-696. https://doi.org/10.3855/jidc.8871
Section
Original Articles

Keywords

RSV, LRTI, children, risk factor